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Preclinical Gastroenterology Studies

BioLegacy’s areas of expertise include:

Colitis / Inflammatory Bowel Disease

Colitis / Inflammatory Bowel Disease

BioLegacy offers extensively characterized colitis models to match your compound’s target pathway. Our expertise in models of gut inflammation ensures a definitive assessment of your therapeutic’s ability to restore mucosal integrity and resolve the underlying inflammatory cascade, delivering pivotal, translatable efficacy data to de-risk your pipeline.

  • DSS-Induced Colitis: An acute, robust model of innate immunity-driven epithelial injury, ideal for rapidly evaluating therapeutics that target mucosal barrier repair and innate inflammatory pathways.
  • Oxazolone-Induced Colitis: A Th2-dominant, T-cell mediated model of colitis that recapitulates key features of ulcerative colitis, best suited for assessing targeted immunomodulatory agents.
Don’t see a model you need? Our portfolio of validated models expands all the time. Ask us - we might have it!
Your competitors aren’t waiting to start their studies.
  • Study design support
  • GLP or non-GLP studies
  • Advanced bioanalytical capabilities
  • Extensive toxicological evaluations
  • Rapid study initiation - usually in under 2 weeks
Contact us and let’s start your study!